IOCB Most Significant Publications 2015

The most significant publications are selected annually by an external international panel of reviewers and the IOCB director.

The awarded publications are listed in their respective clusters alphabetically by title.

• Šámal, M.; Chercheja, S.; Rybáček, J.; Vacek Chocholoušová, J.; Vacek, J.; Bednárová, L.; Šaman, D.; Stará, I. G.; Starý, I. An Ultimate Stereocontrol in Asymmetric Synthesis of Optically Pure Fully Aromatic Helicenes. J. Am. Chem. Soc. 2015, 137, 8469-8474. https://doi.org/10.1021/jacs.5b02794
• Wen, J.; Havlas, Z.; Michl, J. Captodatively Stabilized Biradicaloids as Chromophores for Singlet Fission. J. Am. Chem. Soc. 2015, 137, 165-172. https://doi.org/10.1021/ja5070476
• Mason, P. E.; Uhlig, F.; Vaněk, V.; Buttersack, T.; Bauerecker, S.; Jungwirth, P. Coulomb explosion during the early stages of the reaction of alkali metals with water. Nat. Chem. 2015, 7, 250-254. https://doi.org/10.1038/nchem.2161
• Wu, T.; Kapitán, J.; Mašek, V.; Bouř, P. Detection of Circularly Polarized Luminescence of a Cs-EuIII Complex in Raman Optical Activity Experiments. Angew. Chem. Int. Edit. 2015, 54, 14933-14936. https://doi.org/10.1002/anie.201508120
• Buček, A.; Matoušková, P.; Vogel, H.; Šebesta, P.; Jahn, U.; Weißflog, J.; Svatoš, A.; Pichová, I. Evolution of moth sex pheromone composition by a single amino acid substitution in a fatty acid desaturase. Proc. Natl. Acad. Sci. U. S. A. 2015, 112, 12586-12591. https://doi.org/10.1073/pnas.1514566112
• Mejdrová, I.; Chalupská, D.; Kögler, M.; Šála, M.; Plačková, P.; Baumlová, A.; Hřebabecký, H.; Procházková, E.; Dejmek, M.; Guillon, R.; Strunin, D.; Weber, J.; Lee, G.; Birkus, G.; Mertlíková-Kaiserová, H.; Boura, E.; Nencka, R. Highly Selective Phosphatidylinositol 4-Kinase IIIβ Inhibitors and Structural Insight into Their Mode of Action. J. Med. Chem. 2015, 58, 3767-3793. https://doi.org/10.1021/acs.jmedchem.5b00499
• Tesina, P.; Čermáková, K.; Hořejší, M.; Procházková, K.; Fábry, M.; Sharma, S.; Christ, F.; Demeulemeester, J.; Debyser, Z.; Rijck, J. D.; Veverka, V.; Řezáčová, P. Multiple cellular proteins interact with LEDGF/p75 through a conserved unstructured consensus motif. Nat. Commun. 2015, 6, 7968. https://doi.org/10.1038/ncomms8968
• Petrová, M.; Páv, O.; Buděšínský, M.; Zborníková, E.; Novák, P.; Rosenbergová, Š.; Pačes, O.; Liboska, R.; Dvořáková, I.; Šimák, O.; Rosenberg, I. Straightforward Synthesis of Purine 4′-Alkoxy-2′-deoxynucleosides: First Report of Mixed Purine–Pyrimidine 4′-Alkoxyoligodeoxynucleotides as New RNA Mimics. Org. Lett. 2015, 17, 3426-3429. https://doi.org/10.1021/acs.orglett.5b01430
• Tykvart, J.; Bařinka, C.; Svoboda, M.; Navrátil, V.; Souček, R.; Hubálek, M.; Hradilek, M.; Šácha, P.; Lubkowski, J.; Konvalinka, J. Structural and Biochemical Characterization of a Novel Aminopeptidase from Human Intestine*. J. Biol. Chem. 2015, 290, 11321-11336. https://doi.org/10.1074/jbc.M114.628149
• Amatov, T.; Pohl, R.; Císařová, I.; Jahn, U. Synthesis of Bridged Diketopiperazines by Using the Persistent Radical Effect and a Formal Synthesis of Bicyclomycin. Angew. Chem. Int. Edit. 2015, 54, 12153-12157. https://doi.org/10.1002/anie.201504883
• Kaletová, E.; Kohutová, A.; Hajduch, J.; Kaleta, J.; Bastl, Z.; Pospíšil, L.; Stibor, I.; Magnera, T. F.; Michl, J. The Scope of Direct Alkylation of Gold Surface with Solutions of C1–C4 n-Alkylstannanes. J. Am. Chem. Soc. 2015, 137, 12086-12099. https://doi.org/10.1021/jacs.5b07672
• Schimer, J.; Pávová, M.; Anders, M.; Pachl, P.; Šácha, P.; Cígler, P.; Weber, J.; Majer, P.; Řezáčová, P.; Kräusslich, H.-G.; Müller, B.; Konvalinka, J. Triggering HIV polyprotein processing by light using rapid photodegradation of a tight-binding protease inhibitor. Nat. Commun. 2015, 6, 6461. https://doi.org/10.1038/ncomms7461