Results and publications
2024
12. Gracias, F.; Pohl, R.; Sýkorová, V.; Hocek, M. Bacteriophage-related epigenetic natural and non-natural pyrimidine nucleotides and their influence on transcription with T7 RNA polymerase. Commun. Chem. 2024, 7, 256. DOI:10.1038/s42004-024-01354-5
11. Kovaľ, T.; Borah, N.; Sudzinová, P.; Brezovská, B.; Šanderová, H.; Vaňková Hausnerová, V.; Křenková, A.; Hubálek, M.; Trundová, M.; Adámková, K.; Dušková, J.; Schwarz, M.; Wiedermannová, J.; Dohnálek, J.; Krásný, L.; Kouba, T. Mycobacterial HelD connects RNA polymerase recycling with transcription initiation. Nat. Commun. 2024, 15, 8740. DOI:10.1038/s41467-024-52891-5
10. Linhartova, K.; Falginella, F. L.; Matl, M.; Sebesta, M.; Vácha, R.; Stefl, R. Sequence and structural determinants of RNAPII CTD phase-separation and phosphorylation by CDK7. Nat. Commun. 2024, 15, 9163. DOI:10.1038/s41467-024-53305-2
9. Jendruchová, K.; Gaikwad, S.; Poncová, K.; Gunišová, S.; Valášek, L. S.; Hinnebusch, A. G. Differential effects of 40S ribosome recycling factors on reinitiation at regulatory uORFs in GCN4 mRNA are not dictated by their roles in bulk 40S recycling. Commun. Biol. 2024, 7, 1083. DOI:10.1038/s42003-024-06761-x
8. Keown, J.; Baazaoui, A.; Šebesta, M.; Štefl, R.; Carrique, L.; Fodor, E.; Grimes, J. M. Structural and functional characterization of the interaction between the influenza A virus RNA polymerase and the CTD of host RNA polymerase II. J. Virol. 2024, 98, e00138-24. DOI:10.1128/jvi.00138-24
7. Potužník, J. F.; Cahova, H. If the 5’ cap fits (wear it) – Non-canonical RNA capping. RNA Biol. 2024, 21, 1–13. DOI:10.1080/15476286.2024.2372138
6. Volek, M.; Kurfürst, J.; Kožíšek, M.; Srb, P.; Veverka, V.; Curtis, E.A. Apollon: a deoxyribozyme that generates a yellow product. Nucleic Acids Res. 2024, gkae490. DOI:10.1093/nar/gkae490
5. Volek, M.; Kurfürst, J.; Drexler, M.; Svoboda, M.; Srb, P.; Veverka, V.; Curtis, E.A. Aurora: a fluorescent deoxyribozyme for high-throughput screening. Nucleic Acids Res. 2024, gkae467. DOI:10.1093/nar/gkae467
4. Šoltysová, M.; Škerlová, J.; Pachl, P.; Škubník, K.; Fábry, M.; Sieglová, I.; Farolfi, M.; Grishkovskaya, I.; Babiak, M.; Nováček, J.; Krásný, L.; Řezáčová, P. Structural characterization of two prototypical repressors of SorC family reveals tetrameric assemblies on DNA and mechanism of function. Nucleic Acids Res. 2024, gkae434. DOI:10.1093/nar/gkae434
3. Benoni, B.; Potužník, J. F.; Škríba, A.; Benoni, R.; Trylcova, J.; Tulpa, M.; Spustová, K.; Grab, K.; Mititelu, M.-B.; Pačes, J.; Weber, J.; Stanek, D.; Kowalska, J.; Bednarova, L.; Keckesova, Z.; Vopalensky, P.; Gahurova, L.; Cahova, H. HIV-1 Infection Reduces NAD Capping of Host Cell snRNA and snoRNA. ACS Chem. Biol. 2024. DOI:10.1021/acschembio.4c00151
2. Brunderová, M.; Havlíček, V.; Matyašovský, J.; Pohl, R.; Poštová Slavětínská, L.; Krömer, M.; Hocek, M. Expedient production of site specifically nucleobase-labelled or hypermodified RNA with engineered thermophilic DNA polymerases. Nat. Commun. 2024, 15, 3054. DOI:10.1038/s41467-024-47444-9
1. Smirnova, A. M.; Hronová, V.; Mohammad, M. P.; Herrmannová, A.; Gunišová, S.; Petráčková, D.; Halada, P.; Coufal, Š.; Świrski, M.; Rendleman, J.; Jendruchová, K.; Hatzoglou, M.; Beznosková, P.; Vogel, C.; Valášek, L. S. Stem-loop-induced ribosome queuing in the uORF2/ATF4 overlap fine-tunes stress-induced human ATF4 translational control. Cell Rep. 2024, 43. DOI:10.1016/j.celrep.2024.113976