Václav Veverka

vaclav.veverka@uochb.cas.cz

+420 220 183 135

Group leader

Václav Veverka Group

Chromatin Structural Biology

Profile

Joint laboratory

Laboratory of Structural Biology of Transcription Regulation, Charles University

Positions

2022	Associate Professor in Genetics, Molecular Biology and Virology, Charles University, Faculty of Science, Prague, Czech Republic
2018	Assistant Professor, Charles University, Faculty of Science, Prague, Czech Republic
since 2018	Head of the Laboratory of Structural Biology of Transcription Regulation, Charles University, Faculty of Science, Department of Cell Biology, Prague, Czech Republic
since 2012	Senior PI, IOCB Prague, Structural Biology, Program leader for Biomolecular NMR
2009-2012	Industrial research fellow, University of Leicester, United Kingdom
2003-2009	Postdoctoral fellow, University of Leicester, United Kingdom

All publications

Selected papers

Multiple cellular proteins interact with LEDGF/p75 through a conserved unstructured consensus motif

P. Těšina K. Čermáková M. Hořejší K. Procházková M. Fábry S. Sharma F. Christ J. Demeulemeester Z. Debyser J. De Rijck V. Veverka P. Řezáčová

Nature Communications 6: 7968 (2015)

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Dominant-negative SMARCA4 mutants alter the accessibility landscape of tissue-unrestricted enhancers

H. C. Hodges B. Z. Stanton K. Čermáková C. Y. Chang E. L. Miller J. G. Kirkland W. L. Ku V. Veverka K. Zhao G. R. Crabtree

Nature Structural & Molecular Biology 25 (1): 61-72 (2018)

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Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation

S. Sharma K. Čermáková J. De Rijck J. Demeulemeester M. Fábry S. El Ashkar S. Van Belle M. Lepšík P. Těšina V. Duchoslav P. Novák M. Hubálek P. Srb F. Christ P. Řezáčová H. C. Hodges Z. Debyser V. Veverka

Proceedings of the National Academy of Sciences of the United States of America 115 (30): E7053-E7062 (2018)

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A ubiquitous disordered protein interaction module orchestrates transcription elongation

K. Čermáková J. Demeulemeester V. Lux M. Nedomová S. R. Goldman E. A. Smith P. Srb R. Hexnerová M. Fábry M. Mádlíková M. Hořejší J. De Rijck Z. Debyser K. Adelman H. C. Hodges V. Veverka

Science 374 (6571): 1113-1121 (2021)

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All publications

Latest publications

Rational fragment-based design of compounds targeting the PWWP domain of the HRP family

T. Vantieghem N. A. Aslam E. M. Osipov M. Akele S. Van Belle S. Beelen M. Drexler T. Paulovčáková V. Lux D. Fearond A. Douangamath F. von Delft F. Christ V. Veverka P. Verwilst A. Van Aerschot Z. Debyser S. V. Strelkov

European Journal of Medicinal Chemistry 280: 116960 (2024)

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Structural basis of MICAL autoinhibition

M. Horváth A. Schröfel K. Kowalska J. Sabo J. Vlasák F. Nourisanami M. Sobol D. Pinkas K. Knapp N. Koupilová J. Nováček V. Veverka Z. Lánský D. Rozbeský

Nature Communications 15: 9810 (2024)

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NMR screen reveals the diverse structural landscape of a G-quadruplex library

R. Sgallová M. Volek J. Kurfürst P. Srb V. Veverka E. A. Curtis

Chemistry - A European Journal 2024: Early View

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Aurora: a fluorescent deoxyribozyme for high-throughput screening

M. Volek J. Kurfürst M. Drexler M. Svoboda P. Srb V. Veverka E. A. Curtis

Nucleic Acids Research 52 (15): 9049–9061 (2024)

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Václav Veverka

Profile

Selected papers

Latest publications