Profil

Pozice


2022Docent v oboru genetika, molekulární biologie a virologie, Univerzita Karlova v Praze, Přírodovědecká fakulta
2018 Odborný asistent, Univerzita Karlova v Praze, Přírodovědecká fakulta
od 2018Vedoucí Laboratoře strukturní biologie transkripční regulace, Univerzita Karlova, Přírodovědecká fakulta, Katedra buněčné biologie
od 2012Seniorní vědecký pracovník, IOCB Praha, Strukturní biologie, vedoucí programu biomolekulární NMR
2009-2012Industrial research fellow, University of Leicester, Velká Británie
2003-2009Postdoctoral fellow, University of Leicester, Velká Británie

Vybrané publikace

Multiple cellular proteins interact with LEDGF/p75 through a conserved unstructured consensus motif
Nature Communications 6: 7968 (2015)
Dominant-negative SMARCA4 mutants alter the accessibility landscape of tissue-unrestricted enhancers
Nature Structural & Molecular Biology 25 (1): 61-72 (2018)
Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation
Proceedings of the National Academy of Sciences of the United States of America 115 (30): E7053-E7062 (2018)

Nejnovější publikace

Aurora: a fluorescent deoxyribozyme for high-throughput screening
Nucleic Acids Research 2024: Early View
Apollon: a deoxyribozyme that generates a yellow product
Nucleic Acids Research 2024: Early View
Genomic context-dependent histone H3K36 methylation by three Drosophila methyltransferases and implications for dedicated chromatin readers
Nucleic Acids Research 2024: Early View
The Impact of Lens Epithelium-Derived Growth Factor p75 Dimerization on Its Tethering Function
Cells 13 (3): 227 (2024)