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Publications
All publications
Enantioselective Lanthanide Binding Modulates Collagen Self-Assembly
Aggregate 7 (2): e70293 (2026)
Collagen fibrillogenesis underlies the structural and mechanical properties of the extracellular matrix in connective and other tissues, yet its molecular mechanism remains poorly understood. Here, we show that a europium(III) dipicolinate complex (EuDPA) acts as a luminescent reporter of collagen aggregation. We combine Raman microscopy, circularly polarized luminescence (CPL), and molecular dynamics (MD) simulations to study this process. While Raman imaging directly visualizes the EuDPA-enhanced fibrillar architecture, CPL reveals enantioselective EuDPA–collagen interactions that accompany the fibrillogenesis. MD simulations indicate the presence of stabilizing interactions between hydroxyproline residues and the dipicolinate ligand. The results pave the way to monitoring of protein aggregation in general, and are relevant to fibrotic pathologies and biomimetic materials design.
Trapping SARS-CoV-2 main protease into transient artificial zymogens for high-yield expression and simplified purification
International Journal of Biological Macromolecules 349: 150827 (2026)
Cucurbit[7]uril as a universal anchor for photoswitchable monolayers on gold
Chemical Science 17 (8): 3991–3997 (2026)
Steroidal A/B-ring fusion as a strategy for isoform-selective inhibition of human carbonic anhydrases
RSC Advances 16 (11): 9743–9755 (2026)
Bayesian Learning for Accurate and Robust Biomolecular Force Fields
Journal of Chemical Theory and Computation 2026: Early View