Dominika Chalupská

All publications

Latest publications

Structural and functional insights in flavivirus NS5 proteins gained by the structure of Ntaya virus polymerase and methyltransferase

K. Krejčová P. Krafčíková M. Klíma D. Chalupská K. Chalupský E. Žilecká E. Bouřa

Structure 2024: Early View

Fluorinated cGAMP analogs, which act as STING agonists and are not cleavable by poxins: Structural basis of their function

M. Klíma M. Dejmek V. Duchoslav A. Eisenreichová M. Šála K. Chalupský D. Chalupská B. Novotná G. Birkuš R. Nencka E. Bouřa

Structure 32 (4): 433–439.e4 (2024)

Design, synthesis and evaluation of novel thieno[2,3d]pyrimidine derivatives as potent and specific RIPK2 inhibitors

M. Misehe M. Šála M. Matoušová K. Hercík H. Kocek D. Chalupská E. Chaloupecká M. Hájek E. Bouřa H. Mertlíková Kaiserová R. Nencka

Bioorganic and Medicinal Chemistry Letters 97: 129567 (2024)

Exploring positions 6 and 7 of a quinazoline-based scaffold leads to changes in selectivity and potency towards RIPK2/3 kinases

M. Misehe M. Matoušová K. Hercík K. Škach D. Chalupská M. Dejmek M. Šála M. Hájek E. Bouřa H. Mertlíková-Kaiserová R. Nencka

European Journal of Medicinal Chemistry 260: 115717 (2023)