CS
Milan Vrábel, Ph.D.

Milan Vrábel, Ph.D.

mail milan.vrabelinvalid-email-name@invalid-email-domainuochb.cas.cz
phone +420 220 183 317
Group leader
Milan Vrábel Group
Chemistry of Bioconjugates

Profile

Education
2004-2008
Ph.D. in Organic Chemistry at the Institute of Organic Chemistry and Biochemistry, ASCR, Prague, under supervision of Prof. Dr. Michal Hocek.
2002-2004
Ing. (M.Sc. equivalent) in Chemistry at the Slovak University of Technology in Bratislava, Department of Organic Chemistry, under supervision of Prof. Dr. Ľubor Fišera.
Experience
Since 2014
Head of Junior Research Group, Institute of Organic Chemistry and Biochemistry, ASCR, Prague
2008-2014
Postdoctoral fellow at LMU Munich in the group of Prof. Dr. Thomas Carell with LMU Research Fellowship (2009 and 2011)
All publications

Latest publications

Synthesis of C3-Substituted N1-tert-Butyl 1,2,4-Triazinium Salts via the Liebeskind–Srogl Reaction for Fluorogenic Labeling of Live Cells
V. Šlachtová S. Bellová M. Vrábel
Journal of Organic Chemistry 89 (20): 14634–14640 (2024)
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Transforming Aryl-Tetrazines into Bioorthogonal Scissors for Systematic Cleavage of trans-Cyclooctenes
M. Wilkovitsch W. Kuba P. Keppel B. Sohr A. Löffler S. Kronister A. Fernandez del Castillo M. Goldeck R. Dzijak M. Rahm M. Vrábel D. Svatunek J. Carlson H. Mikula
Angewandte Chemie International Edition 2024: Early View
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Sulfonated Hydroxyaryl-Tetrazines with Increased pKa for Accelerated Bioorthogonal Click-to-Release Reactions in Cells
M. Rahm P. Keppel R. Dzijak M. Dračínský V. Šlachtová S. Bellová P. E. Reyes Gutierrez S. Štěpánová J. E. Raffler E. Tloušťová H. Mertlíková-Kaiserová H. Mikula M. Vrábel
Angewandte Chemie International Edition 2024: Early View
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Bioorthogonal Cycloadditions of C3-Trifluoromethylated 1,2,4-Triazines with trans-Cyclooctenes
V. Šlachtová V. Motornov P. Beier M. Vrábel
Chemistry - A European Journal 30 (40): e202400839 (2024)
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