CS
Dr. Jiří Rybáček

Dr. Jiří Rybáček

mail jiri.rybacekinvalid-email-name@invalid-email-domainuochb.cas.cz
phone +420 220 183 226
Scientist
Ivo Starý Group
Chemistry of Functional Molecules

Profile

Research Interests

organic synthesis, flow chemistry, chiral separations, HPLC and SFC, electron microscopy

Education

2008

Ph.D. in Organic Chemistry, Faculty of Chemical Technology, University of Chemistry and Technology, Prague, under supervision of Dr. Petr Holý at the Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague

2006

Erasmus internship at the University of Copenhagen, Denmark, Department of Chemistry, under supervision of Prof. Mogens Brøndsted Nielsen

2003

M.Sc. in Organic Chemistry, Faculty of Chemical Technology, University of Chemistry and Technology, Prague, under supervision of Assoc. Prof. Stanislav Böhm

Chronology of Employment

since 2003

Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague, Ivo Starý Group, Current Position: Research Scientist 

Publications

34 original papers / h-index: 15

All publications

Selected papers

Racemic and Optically Pure Heptahelicene-2-carboxylic Acid: Its Synthesis and Self-Assembly into Nanowire-Like Aggregates
Racemic and Optically Pure Heptahelicene-2-carboxylic Acid: Its Synthesis and Self-Assembly into Nanowire-Like Aggregates
J. Rybáček I. G. Stará I. Starý P. Rahe M. Nimmrich A. Kühnle
European Journal of Organic Chemistry 2011 (5): 853-860
Heptahelicene‐2‐carboxylic acid was effectively synthesised from suitably functionalised naphthalene building blocks. Methoxy‐substituted 1,1′‐ethyne‐1,2‐diylbis(2‐but‐3‐yn‐1‐ylnaphthalene) was cyclised in the presence of CpCo(CO)2/PPh3 to 2‐methoxy‐7,8,11,12‐tetrahydroheptahelicene, which was converted into heptahelicen‐2‐yl trifluoromethanesulfonate. This reactive intermediate underwent Pd(OAc)2/dppp‐catalysed methoxycarbonylation reaction to provide, after hydrolysis, heptahelicene‐2‐carboxylic acid. The racemate was resolved into enantiomers by semipreparative HPLC on a chiral column. The helicity of (+)‐(P)‐heptahelicene‐2‐carboxylic acid was assigned by correlating its CD spectrum to that of the known (+)‐(P)‐heptahelicene. Racemic heptahelicene‐2‐carboxylic acid was deposited on calcite (10‐14) to undergo self‐assembly into nanowire‐like aggregates as demonstrated by noncontact atomic force microscopy (NC‐AFM).
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Tetrathiafulvalene-functionalized triptycenes: synthetic protocols and elucidation of intramolecular Coulomb repulsions in the oxidized species
J. Rybáček M. Rybáčková M. Hoj M. Bělohradský P. Holý K. Kilsa M. B. Nielsen
Tetrahedron 63 (36): 8840-8854 (2007)
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Synthesis of Extended Bifunctional Triptycenes
J. Rybáček J. Závada P. Holý
Synthesis 2008 (22): 3615-3618
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All publications

Latest publications

Stereocontrolled Synthesis of Chiral Helicene-Indenido ansa- and Half-Sandwich Metal Complexes and Their Use in Catalysis
T. Edlová J. Rybáček H. Cattey J. Vacek L. Bednárová P. Le Gendre A. T. Normand I. G. Stará I. Starý
Angewandte Chemie International Edition 2024: Early View
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Triptycene-Based Tripodal Molecular Platforms
G. Bastien L. Severa M. Škuta C. Santos Hurtado J. Rybáček V. Šolínová I. Císařová V. Kašička J. Kaleta
Chemistry - A European Journal 30 (56): e202401889 (2024)
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Chlorinated Cubane-1,4-dicarboxylic Acids
A. Křížková G. Bastien I. Rončević I. Císařová J. Rybáček V. Kašička J. Kaleta
Journal of Organic Chemistry 89 (16): 11100–11108 (2024)
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Thermal evaporation as sample preparation for silver–assisted laser desorption/ionization mass spectrometry imaging of cholesterol in amyloid tissues
Š. Strnad V. Vrkoslav A. Mengr O. Fabián J. Rybáček M. Kubánek V. Melenovský L. Maletínská J. Cvačka
Analyst 149 (11): 3152-3160 (2024)
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