Profile

Education
2011–2015
Ph.D. – Doctoral study of Physical Chemistry, Faculty of Science, Charles University in Prague (Ph.D. thesis: The Structure and Properties of Modified Nucleic Acid Components under the supervision of Assoc. Prof. Martin Dračínský, IOCB CAS)
2009–2011
M.Sc. – Master study of Biophysical Chemistry, Faculty of Science, Charles University in Prague (Diploma thesis: Antioxidative Effects of the Analogues of Nucleic Acid Components under the supervision of Dr. Helena Mertlíková-Kaiserová, IOCB CAS)
2006–2009
B.Sc. – Bachelor study of Biochemistry, Faculty of Science, Charles University in Prague (Bachelor thesis: The Life Cycle and Metabolic Pathways of the Etiological Agent of Malaria and the Design of a Potential Inhibitor of Hypoxanthin-Guanin-Xanthin- Phosphoribosyl transferase under the supervision of Prof. Antonín Holý, IOCB CAS)
Load more
Experiences
2019
Visiting Fellow, Yokohama National University, Japan. Collaboration with Prof. Akira Naito and Assoc. Prof. Izuru Kawamura, solid-state NMR with in situ irradiation, (3 months)
2018
Postdoctoral Fellow, University of New South Wales, Sydney, Australia. Collaboration with Prof. Martina H. Stenzel and Dr. James M. Hook, solid-state NMR spectroscopy, (9 months)
2016
Postdoctoral Fellow, Technical University Darmstadt, Germany. Collaboration with Prof. Christina M. Thiele, advanced NMR spectroscopy in solution, (12 months)
Scholarships granted
2019
Scholarship from CANON Foundation, financial support of the Japanese stay
2018–2019
Mobility Grant, the Czech Academy of Sciences, financial support of the Australian stay
2017–2018
Postdoctoral Fellowship, the Czech Academy of Sciences
Grants
2021–2023
Czech Science Foundation: NMR Toolbox for Probing Stereochemistry in Phosphorus-Containing Bioactive Molecules

Latest publications

Delivery of N-heterocyclic drugs, acids, phenols, and thiols via Tailor−made Self−immolative linkers
European Journal of Medicinal Chemistry 12: 100216 (2024)
Extending molecular dynamics with dipolar NMR tensors as constraints to chiral phosphorus compounds
Physical Chemistry Chemical Physics 26 (31): 20814-20819 (2024)
Exploring the impact of alignment media on RDC analysis of phosphorus-containing compounds: a molecular docking approach
Physical Chemistry Chemical Physics 26 (3): 2016-2024 (2024)