Hugo Kocek

All publications

Latest publications

Discovery of highly potent SARS-CoV-2 nsp14 methyltransferase inhibitors based on adenosine 5′-carboxamides

H. Kocek D. Chalupská A. Dvořáková M. Zgarbová M. Šála K. Chalupský P. Krafčíková T. Otava M. Drexler E. Procházková B. Klepetářová M. Štefek J. Kozic H. Mertlíková-Kaiserová E. Bouřa J. Weber R. Nencka

RSC Medicinal Chemistry 2024: Early View

Exploring the impact of alignment media on RDC analysis of phosphorus-containing compounds: a molecular docking approach

M. Christou L. Tučková H. Kocek A. Růžička M. Straka E. Procházková

Physical Chemistry Chemical Physics 26 (3): 2016-2024 (2024)

Design, synthesis and evaluation of novel thieno[2,3d]pyrimidine derivatives as potent and specific RIPK2 inhibitors

M. Misehe M. Šála M. Matoušová K. Hercík H. Kocek D. Chalupská E. Chaloupecká M. Hájek E. Bouřa H. Mertlíková Kaiserová R. Nencka

Bioorganic and Medicinal Chemistry Letters 97: 129567 (2024)

Coronaviral RNA-methyltransferases: function, structure and inhibition

R. Nencka J. Šilhán M. Klíma T. Otava H. Kocek P. Krafčíková E. Bouřa

Nucleic Acids Research 50 (2): 635–650 (2022)