Profile

Research interest

Organic synthesis, Organo-Fluorine Chemistry, Asymmetric Synthesis, Reaction Mechanisms, Biocatalysis.

Awards
2013
Alfred Bader Prize for Organic Chemistry
2017
Royal Chemical Society Fluorine Prize
Education
1996-2001
M.Sc. (Dipl. Ing.) in organic chemistry, at the University of Pardubice, Czech Republic.
2001-2004
Ph.D. in Organic Chemistry, under Prof. David O’Hagan at the University of St. Andrews, UK.
Appointments
2005-2006
Postdoctoral fellow with Prof. G. K. Surya Prakash, Loker Hydrocarbon Research Institute, University of Southern California, Los Angeles, USA.
2007-2011
Head of the Junior Research Team, Institute of Organic Chemistry and Biochemistry of the CAS, Prague, Czech Republic.
Since 2012
Head of the Senior Research Group, Institute of Organic Chemistry and Biochemistry of the CAS, Prague, Czech Republic.

Latest publications

From boom to bloom: synthesis of diazidodifluoromethane, its stability and applicability in the ‘click’ reaction
Chemical Communications 5 (61): 885–888 (2025)
Denitrogenative Transformations of NH- and N-Fluoroalkyl-1,2,3-triazoles
Denitrogenative Transformation of Nitrogen Heterocycles (Pazhamalai Anbarasan, Ed.), 211-216, Wiley-VCH (2025)
Synthesis of [6,5,5]Ring-Fused Tricyclic Triazoles by Copper-Promoted Double Cyclization
European Journal of Organic Chemistry 27 (45): e202400736 (2024)
Transformation of 5-acylated N-fluoroalkyl-1,2,3-triazoles to trifluoromethylated ring-fused isoquinolines, 1,3-oxazines, and 1,3-oxazin-6-ones via ketenimines
RSC Advances 14 (37): 26938-26942 (2024)