![Zvaná přednáška – Venki Ramakrishnan](/upload/files/d9/db/d9db6c21ee2b05e7f5eea5f19c544aeaf26a3c56.jpg)
Prof. Venki Ramakrishnan (MRC Laboratory of Molecular Biology, Cambridge, Spojené království)
Termination of Translation in Bacteria and Eukaryotes
15. dubna 2019, 10:00
Přednáškový sál ÚOCHB (budova A, 2. NP, A2.01)
Abstrakt
Termination of translation in all domains of life is triggered by the entry of a stop codon in the A site of the ribosome. These three codons are recognized by a protein release factor. However, release factors in bacteria and eukaryotes appear to have no structural or sequence similarity. In this talk, I will describe structural work that sheds the basis of release factor function in the two domains of life and show that despite their dissimilarity, they share certain common features.
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