Silhan J, Fajtova P, Bartosova J, Hurysz BM, Almaliti J, Miyamoto Y, Eckmann L, Gerwick WH, O'Donoghue AJ, Boura E. (2024) Structural elucidation of recombinant Trichomonas vaginalis 20S proteasome bound to covalent inhibitors Nat Commun.

Silhan J, Klima M, Otava T, Skvara P, Chalupska D, Chalupsky K, Kozic J, Nencka R, Boura E. (2023) Discovery and structural characterization of monkeypox virus methyltransferase VP39 inhibitors reveal similarities to SARS-CoV-2 nsp14 methyltransferase Nat Commun.

Huskova A, Dinesh DC, Srb P, Boura E, Veverka V, Silhan J. (2022) Model of abasic site DNA cross-link repair; from the architecture of NEIL3 DNA binding domains to the X-structure model Nucleic Acids Res.

Nencka R, Silhan J, Klima M, Otava T, Kocek H, Krafcikova P, Boura E. (2022) Coronaviral RNA-methyltransferases: function, structure and inhibition. Nucleic Acids Res..

Krafcikova P, Silhan J, Nencka R, Boura E. (2020) Structural analysis of the SARS-CoV-2 methyltransferase complex involved in RNA cap creation bound to sinefungin Nat Commun.

Smola M, Gutten O, Dejmek M, Kožíšek M, Evangelidis T, Tehrani ZA, Novotná B, Nencka R, Birkuš G, Rulíšek L, Boura E. (2021) Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein. Angewandte.

Dinesh DC, Chalupska D, Silhan J, Koutna E, Nencka R, Veverka V, Boura E. (2020) Structural basis of RNA recognition by the SARS-CoV-2 nucleocapsid phosphoprotein PloS Pathog.

84. Silhan J, Fajtova P, Bartosova J, Hurysz BM, Almaliti J, Miyamoto Y, Eckmann L, Gerwick WH, O'Donoghue AJ, Boura E. Structural elucidation of recombinant Trichomonas vaginalis 20S proteasome bound to covalent inhibitors. Nat Commun. 2024

83. Kocek H, Chalupská D, Dejmek M, Dvoráková A, Zgarbová M, Šála M, Chalupský K, Krafcíková P, Otava T, Drexler M, Procházková E, Klepetárová B, Štefek M, Kozic J, Mertlíková-Kaiserová H, Boura E , Weber J, Nencka Discovery of highly potent SARS-CoV-2 nsp14 methyltransferase inhibitors based on adenosine 5'-carboxamides. RSC Med Chem. 2024

82. Zilecka E, Klima M, Stefek M, Dejmek M, Nencka R, Boura E. Structure of SARS-CoV-2 MTase nsp14 with the inhibitor STM957 reveals inhibition mechanism that is shared with a poxviral MTase VP39.J Struct Biol X. 2024

81. Krejcová K, Krafcikova P, Klima M, Chalupska D, Chalupsky K, Zilecka E, Boura E. Structural and functional insights in flavivirus NS5 proteins gained by the structure of Ntaya virus polymerase and methyltransferase. Structure. 2024

80. Tóth LJ, Krejcová K, Dejmek M, Žilecká E, Klepetárová B, Poštová Slavetínská L, Boura E , Nencka R. Novel analogues of a nonnucleoside SARS-CoV-2 RdRp inhibitor as potential antivirotics. Beilstein J Org Chem.

79. Klima M, Dejmek M, Duchoslav V, Eisenreichova A, Sala M, Chalupsky K, Chalupska D, Novotná B, Birkuš G, Nencka R, Boura E. Fluorinated cGAMP analogs, which act as STING agonists and are not cleavable by poxins: Structural basis of their function. Structure. 2024

2023

78. Misehe M, Matoušová M, Dvoráková A, Hercík K, Škach K, Chalupská D, Dejmek M, Šála M, Hájek M, Boura E , Mertlíková-Kaiserová H, Nencka R. (2023) Exploring positions 6 and 7 of a quinazoline-based scaffold leads to changes in selectivity and potency towards RIPK2/3 kinases. Eur J Med Chem.

77. Dejmek M, Brazdova A, Otava T, Polidarova MP, Klíma M, Smola M, Vavrina Z, Budešínský M, Dracínský M, Liboska R, Boura E , Birkuš G, Nencka R. (2023) Vinylphosphonate-based cyclic dinucleotides enhance STING-mediated cancer immunotherapy. Eur J Med Chem.

76. Eisenreichova A, Klima M, Anila MM, Koukalova A, Humpolickova J, Rózycki B, Boura E. (2023) Crystal Structure of the ORP8 Lipid Transport ORD Domain: Model of Lipid Transport. Cells.

75. Skvara P, Chalupska D, Klima M, Kozic J, Silhan J, Boura E. (2023) Structural basis for RNA-cap recognition and methylation by the mpox methyltransferase VP39. Antiviral Res.

74. Duchoslav V, Boura E. (2023) Structure of monkeypox virus poxin: implications for drug design. Arch Virol.

73. Kortus S, Rehakova K, Klima M, Kolcheva M, Ladislav M, Langore E, Barackova P, Netolicky J, Misiachna A, Hemelikova K, Humpolickova J, Chalupska D, Silhan J, Kaniakova M, Hrcka Krausova B, Boura E , Zapotocky M, Horak M. (2023) Subunit-Dependent Surface Mobility and Localization of NMDA Receptors in Hippocampal Neurons Measured Using Nanobody Probes. J Neurosci.

72. Silhan J, Klima M, Otava T, Skvara P, Chalupska D, Chalupsky K, Kozic J, Nencka R, Boura E. (2023) Discovery and structural characterization of monkeypox virus methyltransferase VP39 inhibitors reveal similarities to SARS-CoV-2 nsp14 methyltransferase Nat Commun.

71. Li F, Ghiabi P, Hajian T, Klima M, Li ASM, Khalili Yazdi A, Chau I, Loppnau P, Kutera M, Seitova A, Bolotokova A, Hutchinson A, Perveen S, Boura E , Vedadi M. (2023) SS148 and WZ16 inhibit the activities of nsp10-nsp16 complexes from all seven human pathogenic coronaviruses. Biochim Biophys Acta.

70. Almaliti J, Fajtová P, Calla J, LaMonte GM, Feng M, Rocamora F, Ottilie S, Glukhov E, Boura E , Suhandynata RT, Momper JD, Gilson MK, Winzeler EA, Gerwick WH, O'Donoghue AJ. (2023) Development of Potent and Highly Selective Epoxyketone-Based Plasmodium Proteasome Inhibitors. Chemistry.

2022

69. Vavrina Z, Perlíková P, Milisavljevic N, Chevrier F, Smola M, Smith J, Dejmek M, Havlícek V, Budešínský M, Liboska R, Vaneková L, Brynda J, Boura E , Rezácová P, Hocek M, Birkuš G. (2022) Design, Synthesis, and Biochemical and Biological Evaluation of Novel 7-Deazapurine Cyclic Dinucleotide Analogues as STING Receptor Agonists. J Med Chem.

68. Misehe M, Klima M, Matoušová M, Chalupská D, Dejmek M, Šála M, Mertlíková-Kaiserová H, Boura E , Nencka R. (2022) Structure-based design and modular synthesis of novel PI4K class II inhibitors bearing a 4-aminoquinazoline scaffold. Bioorg Med Chem Lett.

67. Huskova A, Dinesh DC, Srb P, Boura E, Veverka V, Silhan J. (2022) Model of abasic site DNA cross-link repair; from the architecture of NEIL3 DNA binding domains to the X-structure model Nucleic Acids Res.

66. Klima M, Khalili Yazdi A, Li F, Chau I, Hajian T, Bolotokova A, Kaniskan HÜ, Han Y, Wang K, Li D, Luo M, Jin J, Boura E , Vedadi M. (2022) Crystal structure of SARS-CoV-2 nsp10-nsp16 in complex with small molecule inhibitors, SS148 and WZ16. Protein Sci.

65. Eisenreichova A, Boura E. (2022) Structural basis for SARS-CoV-2 nucleocapsid (N) protein recognition by 14-3-3 proteins. J Struct Biol.

64. Rózycki B, Boura E. (2022) Conformational ensemble of the full-length SARS-CoV-2 nucleocapsid (N) protein based on molecular simulations and SAXS data. Biophys Chem.

63. Dejmek M, Šála M, Brazdova A, Vanekova L, Smola M, Klíma M, Brehová P, Budešínský M, Dracínský M, Procházková E, Zavrel M, Šimák O, Páv O, Boura E , Birkuš G, Nencka R. (2022) Discovery of isonucleotidic CDNs as potent STING agonists with immunomodulatory potential. Structure.

62. Holoubek J, Bednárová K, Haviernik J, Huvarová I, Dvoráková Z, Cerný J, Outlá M, Salát J, Konkolová E, Boura E , Ružek D, Vorlícková M, Eyer L, Renciuk D. (2022) Guanine quadruplexes in the RNA genome of the tick-borne encephalitis virus: their role as a new antiviral target and in virus biology. Nucleic Acids Res.

61. Konkolova E, Krejcová K, Eyer L, Hodek J, Zgarbová M, Fortová A, Jirasek M, Teply F, Reyes-Gutierrez PE, Ružek D, Weber J, Boura E. (2022) A Helquat-like Compound as a Potent Inhibitor of Flaviviral and Coronaviral Polymerases. Molecules.

60. Huskova A, Landova B, Boura E , Silhan J. (2022) The rate of formation and stability of abasic site interstrand crosslinks in the DNA duplex. DNA Repair.

59. Nencka R, Silhan J, Klima M, Otava T, Kocek H, Krafcikova P, Boura E. (2022) Coronaviral RNA-methyltransferases: function, structure and inhibition. Nucleic Acids Res.

2021

58. Gulluni F, Prever L, Li H, Krafcikova P, Corrado I, Lo WT, Margaria JP, Chen A, De Santis MC, Cnudde SJ, Fogerty J, Yuan A, Massarotti A, Sarijalo NT, Vadas O, Williams RL, Thelen M, Powell DR, Schueler M, Wiesener MS, Balla T, Baris HN, Tiosano D, McDermott BM Jr, Perkins BD, Ghigo A, Martini M, Haucke V, Boura E , Merlo GR, Buchner DA, Hirsch E. (2021) PI(3,4)P2-mediated cytokinetic abscission prevents early senescence and cataract formation. Science.

57. Novotná B, Holá L, Stas M, Gutten O, Smola M, Zavrel M, Vavrina Z, Budešínský M, Liboska R, Chevrier F, Dobiaš J, Boura E , Rulíšek L, Birkuš G. (2021) Enzymatic Synthesis of 3'-5', 3'-5' Cyclic Dinucleotides, Their Binding Properties to the Stimulator of Interferon Genes Adaptor Protein, and Structure/Activity Correlations. B iochemistry.

56. Eisenreichova A, Rózycki B, Boura E, Humpolickova J. (2021) Osh6 Revisited: Control of PS Transport by the Concerted Actions of PI4P and Sac1 Phosphatase Front Mol Biosci.

55. Benoni R, Krafcikova P, Baranowski MR, Kowalska J, Boura E, Cahová H. (2021) Substrate Specificity of SARS-CoV-2 Nsp10-Nsp16 Methyltransferase Viruses.

54. Selvaraj C, Dinesh DC, Krafcikova P, Boura E, Aarthy M, Pravin MA, Singh SK. (2021) Structural Understanding of SARS-CoV-2 Drug Targets, Active Site Contour Map Analysis and COVID-19 Therapeutics Curr Mol Pharmacol.

53. Dejmek M, Konkolová E, Eyer L, Straková P, Svoboda P, Šála M, Krejcová K, Ružek D, Boura E, Nencka R. (2021) Non-Nucleotide RNA-Dependent RNA Polymerase Inhibitor That Blocks SARS-CoV-2 Replication Viruses.

52. Horova V, Landova B, Hodek J, Chalupsky K, Krafcikova P, Chalupska D, Duchoslav V, Weber J, Boura E, Klima M. (2021) Localization of SARS-CoV-2 Capping Enzymes Revealed by an Antibody against the nsp10 Subunit Viruses.

51. Sikdar A, Gupta R, Boura E. (2021) Reviewing Antiviral Research Against Viruses Causing Human Diseases - A Structure Guided Approach Curr Mol Pharmacol.

50. Cihlova B*, Huskova A*, Böserle J, Nencka R, Boura E, Silhan J. (2021) High-Throughput Fluorescent Assay for Inhibitor Screening of Proteases from RNA Viruses Molecules.

49. Otava T, Šála M, Li F, Fanfrlík J, Devkota K, Perveen S, Chau I, Pakarian P, Hobza P, Vedadi M, Boura E, Nencka R. (2021) The Structure-Based Design of SARS-CoV-2 nsp14 Methyltransferase Ligands Yields Nanomolar Inhibitors ACS Infect Dis.

48. Pimková Polidarová M, Brehová P, Kaiser MM, Smola M, Dracínský M, Smith J, Marek A, Dejmek M, Šála M, Gutten O, Rulíšek L, Novotná B, Brázdová A, Janeba Z, Nencka R, Boura E, Páv O, Birkuš G. (2021) Synthesis and Biological Evaluation of Phosphoester and Phosphorothioate Prodrugs of STING Agonist 3',3'-c-Di(2'F,2'dAMP) J. Med. Chem.

47. Dostalik P, Krafcikova P, Silhan J, Kozic J, Chalupska D, Chalupsky K, Boura E. (2021) Structural Analysis of the OC43 Coronavirus 2'-O-RNA Methyltransferase J. Virol.

46. Terrier O, Dilly S, Pizzorno A, Chalupska D, Humpolickova J, Boura E, Berenbaum F, Quideau S, Lina B, Fève B, Adnet F, Sabbah M, Rosa-Calatrava M, Maréchal V, Henri J, Slama-Schwok A. (2021) Antiviral Properties of the NSAID Drug Naproxen Targeting the Nucleoprotein of SARS-CoV-2 Coronavirus Molecules.

45. Smola M, Gutten O, Dejmek M, Kožíšek M, Evangelidis T, Tehrani ZA, Novotná B, Nencka R, Birkuš G, Rulíšek L, Boura E. (2021) Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein. Angewandte.

44. Selvaraj C, Panwar U, Dinesh DC, Boura E, Singh P, Dubey VK, Singh SK. (2021) Microsecond MD Simulation and Multiple-Conformation Virtual Screening to Identify Potential Anti-COVID-19 Inhibitors Against SARS-CoV-2 Main Protease Front. Chem.

43. Vavrina Z, Gutten O, Smola M, Zavrel M, Aliakbar Tehrani Z, Charvát V, Kožíšek M, Boura E, Birkuš G, Rulíšek L. (2021) Protein-Ligand Interactions in the STING Binding Site Probed by Rationally Designed Single-Point Mutations: Experiment and Theory Biochemistry.

42. Milisavljevic N, Konkolová E, Kozák J, Hodek J, Veselovská L, Sýkorová V, Cížek K, Pohl R, Eyer L, Svoboda P, Ružek D, Weber J, Nencka R, Boura E, Hocek M. (2021) Antiviral Activity of 7-Substituted 7-Deazapurine Ribonucleosides, Monophosphate Prodrugs, and Triphoshates against Emerging RNA Viruses ACS Infect Dis.

41. Selvaraj C, Dinesh DC, Panwar U, Boura E, Singh SK. (2021) High-Throughput Screening and Quantum Mechanics for Identifying Potent Inhibitors against Mac1 Domain of SARS-CoV-2 Nsp3 IEEE/ACM Trans Comput Biol Bioinform .

2020

40. Dinesh DC, Chalupska D, Silhan J, Koutna E, Nencka R, Veverka V, Boura E. (2020) Structural basis of RNA recognition by the SARS-CoV-2 nucleocapsid phosphoprotein PloS Pathog.

39. Konkolova E, Dejmek M, Hrebabecký H, Šála M, Böserle J, Nencka R, Boura E.. (2020) Remdesivir triphosphate can efficiently inhibit the RNA-dependent RNA polymerase from various flaviviruses Antiviral Res.

38. Krafcikova P, Silhan J, Nencka R, Boura E. (2020) Structural analysis of the SARS-CoV-2 methyltransferase complex involved in RNA cap creation bound to sinefungin Nat Commun.

37. Selvaraj C, Dinesh DC, Panwar U, Abhirami R, Boura E, Singh SK. (2020) Structure-based virtual screening and molecular dynamics simulation of SARS-CoV-2 Guanine-N7 methyltransferase (nsp14) for identifying antiviral inhibitors against COVID-19 J Biomol Struct Dyn.

36. Konkolova E, Klima M, Nencka R, Boura E. (2020) Structural analysis of the putative SARS-CoV-2 primase complex. J Struct Biol.

35. Pemberton JG, Kim YJ, Humpolickova J, Eisenreichova A, Sengupta N, Toth DJ, Boura E, Balla T. (2020) Defining the subcellular distribution and metabolic channeling of phosphatidylinositol J Cell Biol.

34. Smola M, Horova V, Boura E, Klima M. (2020) Structural basis for hijacking of the host ACBD3 protein by bovine and porcine enteroviruses and kobuviruses Arch Virol.

33. Dinesh DC, Tamilarasan S, Rajaram K, Boura E . (2020) Antiviral Drug Targets of Single-Stranded RNA Viruses Causing Chronic Human Diseases Curr Drug Targets .

2019

32. Novotná B, Vaneková L, Zavrel M, Budešínský M, Dejmek M, Smola M, Gutten O, Tehrani ZA, Pimková Polidarová M, Brázdová A, Liboska R, Štepánek I, Vavrina Z, Jandušík T, Nencka R, Rulíšek L, Boura E, Brynda J, Páv O, Birkuš G. (2019) Enzymatic Preparation of 2'-5',3'-5'-Cyclic Dinucleotides, Their Binding Properties to Stimulator of Interferon Genes Adaptor Protein, and Structure/Activity Correlations J Med Chem.

31. Chalupska D, Rózycki B, Klima M, Boura E . (2019) Structural insights into Acyl-coenzyme A binding domain containing 3 (ACBD3) protein hijacking by picornaviruses. Protein Sci.

30. Smola M, Birkus G, Boura E . (2019) No magnesium is needed for binding of the stimulator of interferon genes to cyclic dinucleotides. Acta Crystallogr F Struct Biol Commun .

29. Dubankova A, Horova V, Klima M, Boura E . (2019) Structures of kobuviral and siciniviral polymerases reveal conserved mechanism of picornaviral polymerase activation. J Struct Biol.

28. Horova V , Lyoo H, Rózycki B, Chalupska D, Smola M, Humpolickova J , Strating JRPM, van Kuppeveld FJM, Boura E , Klima M. (2019) Convergent evolution in the mechanisms of ACBD3 recruitment to picornavirus replication sites. PLoS Pathog.

27. Dubankova A, Boura E . (2019) Structure of the yellow fever NS5 protein reveals conserved drug targets shared among flaviviruses. Antiviral Res.

26. Chalupska D, Rózycki B, Humpolickova J , Faltova L, Klima M, Boura E . (2019) Phosphatidylinositol 4-kinase IIIß (PI4KB) forms highly flexible heterocomplexes that include ACBD3, 14-3-3, and Rab11 proteins. Sci Rep.

25. Sengupta N, Jovic M, Barnaeva E, Kim DW, Hu X, Southall N, Dejmek M, Mejdrova I, Nencka R, Baumlova A, Chalupska D, Boura E , Ferrer M, Marugan J, Balla T. (2019) A large scale high-throughput screen identifies chemical inhibitors of phosphatidylinositol 4-kinase type II alpha. J Lipid Res.

2018

24. Silhan J,* Zhao Q, Boura E, Thomson H, Förster A, Tang CM,* Freemont PS,* Baldwin GS.* (2018) Structural basis for recognition and repair of the 3'-phosphate by NExo, a base excision DNA repair nuclease from Neisseria meningitidis. Nucleic Acids Res .

23. Šebera J#, Dubankova A#, Sychrovský V, Ruzek D, Boura E,* Nencka R.* (2018) The structural model of Zika virus RNA-dependent RNA polymerase in complex with RNA for rational design of novel nucleotide inhibitors. Sci Rep.

22. Sohn M, Korzeniowski M, Zewe JP, Wills RC, Hammond GRV, Humpolickova J, Vrzal L, Chalupska D, Veverka V, Fairn GD, Boura E, Balla T. (2018) PI(4,5)P2 controls plasma membrane PI4P and PS levels via ORP5/8 recruitment to ER-PM contact sites. J Cell Biol .

2017

21. Dubankova A, Humpolickova J, Klima M, Boura E. (2017) Negative charge and membrane-tethered viral 3B cooperate to recruit viral RNA dependent RNA polymerase 3Dpol Sci Rep.

20. Peti W, Page R, Boura E, Rózycki B. (2017) Structures of Dynamic Protein Complexes: Hybrid Techniques to Study MAP Kinase Complexes and the ESCRT System Methods Mol Biol .

19. Chalupska D, Eisenreichova A, Rózycki B, Rezabkova L, Humpolickova J, Klima M, Boura E. (2017) Structural analysis of phosphatidylinositol 4-kinase IIIß (PI4KB) - 14-3-3 protein complex reveals internal flexibility and explains 14-3-3 mediated protection from degradation in vitro J Struct Biol.

18. Hercik K, Brynda J, Nencka R, Boura E. (2017) Structural basis of Zika virus methyltransferase inhibition by sinefungin Arch Virol.

17. Boura E, Baumlova A, Chalupska D, Dubankova A, Klima M. (2017) Metal ions-binding T4 lysozyme as an intramolecular protein purification tag compatible with X-ray crystallography Protein Science

16. Klima M, Chalupska D, Rozycki B,Humpolickova J, Rezabkova L, Silhan J, Baumlova A, Dubankova A, Boura E. (2017) Kobuviral Non-structural 3A Proteins Act as Molecular Harnesses to Hijack the Host ACBD3 Protein Structure

15. Humpolickova J#, Mejdrova I#, Matousova M, Nencka R,* Boura E.* (2017) Fluorescent Inhibitors as Tools To Characterize Enzymes: Case Study of the Lipid Kinase Phosphatidylinositol 4-Kinase IIIß (PI4KB) J Med Chem.

14. Mejdrova I#, Chalupska D# , Plackova P, Muller C, Sala M, Klima M, Baumlova A , Hrebabecky H, Prochazkova E, Dejmek M, Strunin D, Weber J, Lee G, Matousova M, Mertlíkova-Kaiserová H, Ziebuhr J, Birkus G, Boura E,* Nencka R.* (2017) Rational Design of Novel Highly Potent and Selective Phosphatidylinositol 4-Kinase IIIß (PI4KB) Inhibitors as Broad-Spectrum Antiviral Agents and Tools for Chemical Biology J Med Chem.

13. Hercik K , Kozak J, Sala M, Dejmek M, Hrebabecky H, Zbornikova E, Smola M , Ruzek D, Nencka R, Boura E. (2017) Adenosine triphosphate analogs can efficiently inhibit the Zika virus RNA-dependent RNA polymerase Antiviral Res.

2016

12. Eisenreichova A, Klima M, Boura E. (2016) Crystal structures of a yeast 14-3-3 protein from Lachancea thermotolerans in the unliganded form and bound to a human lipid kinase PI4KB-derived peptide reveal high evolutionary conservation Acta Crystallogr F Struct Biol Commun.

11. Baumlova A, Gregor J, Boura E. (2016) The structural basis for calcium inhibition of lipid kinase PI4K IIalpha and comparison with the apo state Physiol Res.

10. Klima M , Tóth DJ, Hexnerova R, Baumlova A, Chalupska D , Tykvart J, Rezabkova L, Sengupta N, Man P, Dubankova A, Humpolickova J , Nencka R, Veverka V, Balla T, Boura E. (2016) Structural insights and in vitro reconstitution of membrane targeting and activation of human PI4KB by the ACBD3 protein Sci Rep.

2015

9. Boura E , Nencka R. (2015) Phosphatidylinositol 4-kinases: Function, structure, and inhibition Exp Cell Res.

8. Klima M, Baumlova A, Chalupska D, Hřebabecký H, Dejmek M, Nencka R, Boura E. (2015) The high-resolution crystal structure of phosphatidylinositol 4-kinase IIß and the crystal structure of phosphatidylinositol 4-kinase IIa containing a nucleoside analogue provide a structural basis for isoform-specific inhibitor design Acta Crystallogr D Biol Crystallogr.

7. Mejdrová I#, Chalupská D# , Kögler M#, Šála M, Plačková P, Baumlová A , Hřebabecký H, Procházková E, Dejmek M, Guillon R, Strunin D, Weber J, Lee G, Birkus G, Mertlíková-Kaiserová H, Boura E *, Nencka R*. (2015) Highly Selective Phosphatidylinositol 4-Kinase IIIß Inhibitors and Structural Insight into Their Mode of Action J Med Chem.

6. Dejmek M, Šála M, Hřebabecký H, Dračínský M, Procházková E, Chalupská D, Klíma M , Plačková P, Hájek M, Andrei G, Naesens L, Leyssen P, Neyts J, Balzarini J, Boura E , Nencka R. (2015) Norbornane-based nucleoside and nucleotide analogues locked in North conformation Bioorg Med Chem.

2014

5. Różycki B, Boura E. (2014) Large, dynamic, multi-protein complexes: a challenge for structural biology J Phys Condens Matter.

4. Baumlova A, Chalupska D, Róźycki B, Jovic M, Wisniewski E, Klima M, Dubankova A, Kloer DP, Nencka R, Balla T, Boura E. (2014) The crystal structure of the phosphatidylinositol 4-kinase IIa EMBO Rep.

3. Jović M, Kean MJ, Dubankova A, Boura E, Gingras AC, Brill JA, Balla T. (2014) Endosomal sorting of VAMP3 is regulated by PI4K2A J Cell Sci.

2013

2. Nemecek D, Plevka P, Boura E (2013) Using cryoEM reconstruction and phase extension to determine crystal structure of bacteriophage ϕ6 major capsid protein Protein J.

1. Nemecek D, Boura E , Wu W, Cheng N, Plevka P, Qiao J, Mindich L, Heymann JB, Hurley JH, Steven AC. (2013) Subunit folds and maturation pathway of a dsRNA virus capsid Structure.

OLD

Rozycki B, Boura E , Hurley JH, Hummer G. (2012) Membrane-elasticity model of Coatless vesicle budding induced by ESCRT complexes PLoS Comput Biol. [PubMed]

Boura E , Ivanov V, Carlson LA, Mizuuchi K, Hurley JH. (2012) Endosomal Sorting Complex Required for Transport (ESCRT) complexes induce phase-separated microdomains in supported lipid bilayers. J Biol Chem. [PubMed]

Baskaran S, Ragusa MJ, Boura E , Hurley JH. (2012) Two-Site Recognition of Phosphatidylinositol 3-Phosphate by PROPPINs in Autophagy. Mol Cell. [PubMed]

Boura E , Rózycki B, Chung HS, Herrick DZ, Canagarajah B, Cafiso DS, Eaton WA, Hummer G, Hurley JH. (2012) Solution structure of the ESCRT-I and -II supercomplex: implications for membrane budding and scission. Structure [PubMed]

Noinaj N, Easley NC, Oke M, Mizuno N, Gumbart J, Boura E , Steere AN, Zak O, Aisen P, Tajkhorshid E, Evans RW, Gorringe AR, Mason AB, Steven AC, Buchanan SK. (2012) Structural basis for iron piracy by pathogenic Neisseria. Nature [PubMed]

Boura E , Hurley JH. (2012) Structural basis for membrane targeting by the MVB12-associated ß-prism domain of the human ESCRT-I MVB12 subunit. PNAS [PubMed]

Boura E , Rozycki B, Herrick D, Chung HS, Vecer J, Eaton W, Cafiso D, Hummer G, and Hurley JH. (2011) Solution structure of the ESCRT-I complex by small angle x-ray scattering, EPR, and FRET spectroscopy PNAS [PubMed]

Hurley JH, Boura E , Carlson LA, Rozycki B. (2010) Membrane budding. Cell [PubMed]

Im YJ, Wollert T, Boura E , Hurley JH. (2009) Structure and function of the ESCRT-II-III interface in multivesicular body biogenesis. Dev Cell. [PubMed]

Boura E , Silhan J, Herman P, Vecer J, Sulc M, Teisinger J, Obsilova V, Obsil T. (2007) Both the N-terminal loop and wing W2 of the forkhead domain of transcription factor Foxo4 are important for DNA binding. J Biol Chem. [PubMed]

Boura E , Liebl D, Spísek R, Fric J, Marek M, Stokrová J, Holán V, Forstová J. (2005) Polyomavirus EGFP-pseudocapsids: analysis of model particles for introduction of proteins and peptides into mammalian cells. FEBS Lett. [PubMed]

Boura publications