Postdoctoral position in synthetic organic chemistry
Chemistry of Natural Products
Job description
The project aims at the development of new amination reactions using persistent nitrogen-centered radicals, for the synthesis of nitrogen-rich small organic molecules. In collaboration, the pharmacological profile of the synthesized molecules will be assessed by patch clamp electrophysiology on voltage gated calcium ion channels. The analgesic properties of the best hit molecules will be assessed in vivo in validated behavioral preclinical pain models.
Requirements
The candidate holds a PhD degree in organic chemistry and has strong expertise in organic chemistry, is interested in methodology development and mechanism elucidation, can independently design and perform syntheses of complex molecules, develop synthetic methodology, has experience with all relevant analytical and lab techniques, and is able to analyze and summarize experimental data. The candidate collaborates and participates in group activities, is organized, self-motivated, and enthusiastic to be part of an organic chemistry project linked to drug discovery and can communicate and write proficiently in English.
We offer
- Competitive financial remuneration (60.000 CZK gross salary)
- 5 weeks of vacation plus 4 days of personal leave
- Collaboration in an international team
- Further education and training
- Financial support for parents with young children who return to work immediately after the maternity/parental leave
- Health insurance and full benefits package incl. contribution to supplementary pension insurance, contribution to sports/culture/leisure time, meals subsidized by the employer, etc.
- Working in a young, promising, and progressive scientific team of organic chemists and biologists.
- State-of-the-art instrumentation portfolio
- Location in the stunning city of Prague
Additional information
full-time fixed-term employment contract initially for 1 year with the potential of extension for another year
1 January 2025
How to apply
All applications should be sent to Dr. Emanuela Jahn at emanuela.jahn@uochb.cas.cz.
The application should consist of a cover letter pointing out your competence and experience with respect to the requirements of this position, CV, PhD degree certificate, publication list and contact information for two referees.
Applications will be reviewed and considered until the position is filled. Suitable candidates will be contacted to arrange an interview. Please note that if you are not contacted within 6 weeks, we have given preference to candidates who more closely meet the criteria. Thank you for your understanding.