![Zvaná přednáška – Lanny S. Liebeskind](/upload/files/fe/8e/fe8e44ba11401d49c2b877cdcdffd8336325f4b1.jpg)
Prof. Lanny S. Liebeskind (Emory University, Atlanta, GA, USA)
Seeking Novel Reactivity and High Selectivity in Modern Organic Synthesis: Studies of the pH-Neutral, Cu-Catalyzed Formation of Carbon-Carbon and Carbon-Heteroatom Bonds and their Application to Biomedically Relevant Synthesis
Abstrakt
Achieving high chemoselectivity in functionally complex systems under mild reaction conditions is a significant 21st century challenge for synthetic scientists. In contrast to biological processes, where exquisite selectivity is achieved in vivo in functionally very complex systems through the fine-tuning of protein structure to function, achieving high chemoselectivity on functionally complex molecules in non-enzymatic systems in vitro requires alternative strategies of control. This lecture will describe new control strategies that have led to the development of novel synthetic methods for pH-neutral carbon-carbon and carbon-heteroatom bond formation from nominally unreactive bond types.
![](/upload/files/c7/2a/c72afe69504ab9d3caa5cc182326b814cdd4846f.jpg)
![](/upload/files/7e/f1/7ef137cfe72180f780f96fe475ee0ff2b58a8930.jpg)
![](/upload/files/d3/2d/d32df7451a1f55fe6dc0d4e488d95236bee6322a.jpg)
![](/upload/files/f8/53/f853fce9df9fe521e8849a92d9ce0682c3461db0.jpg)