Profil

Ocenění
2003
Alfred Bader Prize for Organic Chemistry from the Czech Chemical Society
Vzdělání
1988-1993
Studies of organic chemistry at the Charles University, Prague, Mgr. (equal MSc.) degree
1993-2000

Ph.D. studies at Institute of Organic Chemistry and Biochemistry, Prague and Institute of Chemical Technology, Prague; (1/1999–7/2000 interrupted due to civil service)

Zkušenosti
2002-2003
Postdoctoral studies with Jean-Pierre Sauvage, Université Louis Pasteur, Strasbourg; Individual Marie-Curie Fellowship
2007-2011
Leader of junior research group at  Institute of Organic Chemistry and Biochemistry CAS, Prague
2012-2015
Leader of „Targeted research team“ at  Institute of Organic Chemistry and Biochemistry CAS, Prague, focused on the development of delivery systems for nucleoside triphosphates.
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Nejnovější publikace

Real-time Imaging of Nascent DNA in Live Cells by Monitoring the Fluorescence Lifetime of DNA-Incorporated Thiazole Orange-Modified Nucleotides
Angewandte Chemie International Edition 62 (38): e202307548 (2023)
trans-Cyclooctene- and Bicyclononyne-Linked Nucleotides for Click Modification of DNA with Fluorogenic Tetrazines and Live Cell Metabolic Labeling and Imaging
Bioconjugate Chemistry 34 (4): 772–780 (2023)
Lipid-linked nucleoside triphosphates for enzymatic synthesis of hydrophobic oligonucleotides with enhanced membrane anchoring efficiency
Chemical Science 14 (15): 4059–4069 (2023)
Nucleotides Bearing Red Viscosity-Sensitive Dimethoxy-Bodipy Fluorophore for Enzymatic Incorporation and DNA Labeling
Bioconjugate Chemistry 34 (1): 133–139 (2023)