Radim Nencka, Ph.D.

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Nejnovější publikace

Chapter One - Computational strategies for the design of proteolysis targeting chimera degraders: Artificial intelligence enabled PROTAC design

R. Kamaraj R. Nencka P. Pávek

Annual Reports in Medicinal Chemistry Volume 63 (R. Nencka, Ed.), 1-37, Academic Press (2024)

Discovery of highly potent SARS-CoV-2 nsp14 methyltransferase inhibitors based on adenosine 5′-carboxamides

H. Kocek D. Chalupská A. Dvořáková M. Zgarbová M. Šála K. Chalupský P. Krafčíková T. Otava M. Drexler E. Procházková B. Klepetářová M. Štefek J. Kozic H. Mertlíková-Kaiserová E. Bouřa J. Weber R. Nencka

RSC Medicinal Chemistry 2024: Early View

Structure–activity relationship study of small-molecule inhibitor of Atg12-Atg3 protein–protein interaction

K. Škach J. Böserle G. C. Nuta P. Břehová S. Bialik N. Kozer H. Barr E. Chaloupecká A. Kimchi R. Nencka

Bioorganic and Medicinal Chemistry Letters 112: 129939 (2024)

Structure of SARS-CoV-2 MTase nsp14 with the inhibitor STM957 reveals inhibition mechanism that is shared with a poxviral MTase VP39

E. Žilecká M. Klíma M. Štefek M. Dejmek R. Nencka E. Bouřa

Journal of Structural Biology: X 10: 100109 (2024)